IMPAD1 antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q9NX62 |
Other Accession | NM_017813, NP_060283 |
Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
Predicted | Rat, Rabbit, Chicken, Horse, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 39kDa |
Gene ID | 54928 |
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Alias Symbol | FLJ20421, IMPA3, GPAPP, IMP 3, IMP-3 |
Other Names | Inositol monophosphatase 3, IMP 3, IMPase 3, 3.1.3.25, 3.1.3.7, Golgi 3-prime phosphoadenosine 5-prime phosphate 3-prime phosphatase, Golgi-resident PAP phosphatase, gPAPP, Inositol monophosphatase domain-containing protein 1, Inositol-1(or 4)-monophosphatase 3, Myo-inositol monophosphatase A3, IMPAD1, IMPA3 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-IMPAD1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | IMPAD1 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | BPNT2 (HGNC:26019) |
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Synonyms | IMPA3, IMPAD1 |
Function | Exhibits 3'-nucleotidase activity toward adenosine 3',5'- bisphosphate (PAP), namely hydrolyzes adenosine 3',5'-bisphosphate into adenosine 5'-monophosphate (AMP) and a phosphate. May play a role in the formation of skeletal elements derived through endochondral ossification, possibly by clearing adenosine 3',5'-bisphosphate produced by Golgi sulfotransferases during glycosaminoglycan sulfation. Has no activity toward 3'-phosphoadenosine 5'-phosphosulfate (PAPS) or inositol phosphate (IP) substrates including I(1)P, I(1,4)P2, I(1,3,4)P3, I(1,4,5)P3 and I(1,3,4,5)P4. |
Cellular Location | Golgi apparatus. Golgi apparatus, trans-Golgi network membrane; Single-pass type II membrane protein {ECO:0000255, ECO:0000269|PubMed:18695242}. Note=The catalytic core is predicted to reside within the Golgi lumen |
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Provided below are standard protocols that you may find useful for product applications.
References
Zhang,H.,(2003)Nat.Biotechnol.21(6),660-666ReconstitutionandStorage:Forshorttermuse,storeat2-8Cupto1week.Forlongtermstorage,storeat-20Cinsmallaliquotstopreventfreeze-thawcycles.
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