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>   home   >   Products   >   Primary Antibodies   >   Microbiology   >   UBN1 antibody - C-terminal region   

UBN1 antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - UBN1 antibody - C-terminal region AI12821

    WB Suggested Anti-UBN1 Antibody Titration: 0.2-1 μg/ml
    Positive Control: Hela cell lysate
    UBN1 is supported by BioGPS gene expression data to be expressed in HeLa
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NPG3
Other Accession NM_016936, NP_058632
Reactivity Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 121kDa
Additional Information
Gene ID 29855
Alias Symbol VT, VT4
Other Names Ubinuclein-1, HIRA-binding protein, Protein VT4, Ubiquitously expressed nuclear protein, UBN1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-UBN1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsUBN1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name UBN1
Function Acts as a novel regulator of senescence. Involved in the formation of senescence-associated heterochromatin foci (SAHF), which represses expression of proliferation-promoting genes. Binds to proliferation-promoting genes. May be required for replication- independent chromatin assembly.
Cellular Location Nucleus, nucleoplasm. Nucleus, PML body. Cell junction, tight junction. Note=Localized as a nuclear speckled-like pattern in proliferating primary fibroblasts Colocalizes with HIRA, PML and SP100 in PML bodies of senescent cells. Colocalizes with TJP1 and CLDN1. Detected along the upper granular cell layer of epidermis. When overexpressed, accumulates in the nucleus in cells showing defective cytokinesis
Tissue Location Ubiquitous. Also expressed in numerous tumors and cancer cell lines.
Research Areas
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$ 293.00
Cat# AI12821
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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