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Fxn antibody - middle region

Rabbit Polyclonal Antibody

  • WB - Fxn antibody - middle region AI12861

    WB Suggested Anti-Fxn Antibody Titration: 1.0 μg/ml
    Positive Control: Mouse Heart
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O35943
Other Accession NM_008044, NP_032070
Reactivity Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rabbit, Pig, Chicken, Horse, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 23kDa
Additional Information
Gene ID 14297
Alias Symbol FA, FARR, Frda, X25
Other Names Frataxin, mitochondrial, Fxn,, Frataxin intermediate form, Frataxin mature form, Fxn, Frda
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Fxn antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsFxn antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Fxn
Synonyms Frda
Function Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+); the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activity of ACO1 (By similarity).
Cellular Location Cytoplasm. Mitochondrion Note=PubMed:17597094 describes localization exclusively in mitochondria
Tissue Location Heart, liver, skeletal muscle, kidney, spleen and thymus. Weakly expressed in the brain and lung
Research Areas
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$ 293.00
Cat# AI12861
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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