|Other Accession||NM_177439, NP_803188|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Yeast, Bovine, Dog|
|Predicted||Human, Mouse, Rat, Pig, Horse, Bovine, Dog|
|Alias Symbol||CDLIV, JM23, MRX44, MRX9, SPB1, TRM7|
|Other Names||Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2, 184.108.40.2066, Cap methyltransferase 2, Cap2 2'O-ribose methyltransferase 2, HMTr2, MTr2, FtsJ methyltransferase domain-containing protein 1, Protein adrift homolog, CMTR2, AFT, FTSJD1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-FTSJ1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||FTSJ1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap2 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the second nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) (cap0) to produce m(7)GpppRmpNm (cap2). Recognizes a guanosine cap on RNA independently of its N(7) methylation status. Display cap2 methylation on both cap0 and cap1. Displays a preference for cap1 RNAs.|
|Cellular Location||Nucleus. Cytoplasm. Membrane; Single-pass membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Martin J.,et al.Nature 432:988-994(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Zan Q.,et al.Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases.
Werner M.,et al.Nucleic Acids Res. 39:4756-4768(2011).
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