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Lrrc19 Antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q8BZT5 |
| Other Accession | NM_175305, NP_780514 |
| Reactivity | Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig |
| Predicted | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 41kDa |
| Gene ID | 100061 |
|---|---|
| Alias Symbol | 9130022A01Rik, AI314124, AL022954, AW261791 |
| Other Names | Leucine-rich repeat-containing protein 19, Lrrc19 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Lrrc19 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Lrrc19 Antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Lrrc19 {ECO:0000312|MGI:MGI:2140219} |
|---|---|
| Function | Pathogen-recognition receptor which mediates the activation of TRAF2- and TRAF6 NF-kappa-B signaling pathways and induces the expression of pro-inflammatory cytokines (PubMed:26776522, PubMed:19679103, PubMed:25026888). In kidney, prevents infection by uropathogenic bacteria by inducing the production of cytokines, chemokines and antimicrobial substances (PubMed:25026888). In gut, involved in host-microbiota interactions, plays a critical role in promoting the recruitment of immune cells and intestinal inflammation (PubMed:26776522). |
| Cellular Location | Membrane; Single-pass type I membrane protein |
| Tissue Location | Strongly expressed in kidney, also expressed in spleen, intestine and colon (PubMed:26776522, PubMed:19679103). Highly expressed in epithelial cells (PubMed:26776522). In kidney, mainly expressed in renal collecting duct epithelial cells (PubMed:25026888) |
Research Areas
Citations (0)
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
Carninci P.,et al.Science 309:1559-1563(2005).
Church D.M.,et al.PLoS Biol. 7:E1000112-E1000112(2009).
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$ 389.00
Cat# AI13074
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