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Prkcdbp Antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q91VJ2 |
| Other Accession | NM_028444, NP_082720 |
| Reactivity | Human, Mouse, Rat, Rabbit, Pig, Bovine, Guinea Pig, Dog |
| Predicted | Human, Mouse, Rat, Rabbit, Pig, Bovine, Guinea Pig, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 28kDa |
| Gene ID | 109042 |
|---|---|
| Alias Symbol | 3110015B12Rik, 6330514M23Rik, MGC6598, SRBC |
| Other Names | Protein kinase C delta-binding protein, Cavin-3, Serum deprivation response factor-related gene product that binds to C-kinase, Prkcdbp, Srbc |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Prkcdbp antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Prkcdbp Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Cavin3 |
|---|---|
| Synonyms | Prkcdbp, Srbc |
| Function | Regulates the traffic and/or budding of caveolae (By similarity). Plays a role in caveola formation in a tissue-specific manner. Required for the formation of caveolae in smooth muscle but not in the lung and heart endothelial cells (PubMed:28285351, PubMed:23652019). Regulates the equilibrium between cell surface- associated and cell surface-dissociated caveolae by promoting the rapid release of caveolae from the cell surface (PubMed:25588833). Plays a role in the regulation of the circadian clock. Modulates the period length and phase of circadian gene expression and also regulates expression and interaction of the core clock components PER1/2 and CRY1/2 (PubMed:23079727). |
| Cellular Location | Cytoplasm. Cytoplasm, cytosol. Membrane, caveola Note=Localizes in the caveolae in a caveolin-dependent manner |
| Tissue Location | Lung, heart, skeletal muscle, liver, brain, vascular and urinary bladder smooth muscle (at protein level). Strongly expressed in uterus, ovary, mammary and epithelial cells. Also expressed in spleen, intestine, kidney and testis |
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
Carninci P.,et al.Science 309:1559-1563(2005).
Izumi Y.,et al.J. Biol. Chem. 272:7381-7389(1997).
Villen J.,et al.Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007).
Schneider K.,et al.EMBO Rep. 13:1138-1144(2012).
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$ 389.00
Cat# AI13226
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