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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ASZ1 antibody - middle region   

ASZ1 antibody - middle region

Rabbit Polyclonal Antibody

  • WB - ASZ1 antibody - middle region AI13424

    WB Suggested Anti-ASZ1 Antibody Titration: 1.0 μg/ml
    Positive Control: THP-1 Whole Cell
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8WWH4
Other Accession NM_130768, NP_570124
Reactivity Human, Mouse, Rat, Rabbit, Sheep, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Sheep, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 53kDa
Additional Information
Gene ID 136991
Alias Symbol ALP1, ANKL1, C7orf7, GASZ, MGC26634, Orf3, CT1.19
Other Names Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1, Ankyrin-like protein 1, Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein, ASZ1 (HGNC:1350)
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-ASZ1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsASZ1 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ASZ1 (HGNC:1350)
Function Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi- bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation (By similarity).
Cellular Location Cytoplasm. Note=Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis Specifically localizes to pi-bodies, a subset of the nuage which contains primary piRNAs (By similarity).
Tissue Location Expressed exclusively in the testis and ovary and at higher levels in the adult testis compared with the adult ovary.
Research Areas
Citations (0)

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Yan W.,et al.Mol. Endocrinol. 16:1168-1184(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Scherer S.W.,et al.Science 300:767-772(2003).

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$ 293.00
Cat# AI13424
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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