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>   home   >   Products   >   Primary Antibodies   >   Metabolism   >   OMA1 antibody - middle region   

OMA1 antibody - middle region

Rabbit Polyclonal Antibody

  • WB - OMA1 antibody - middle region AI13463

    WB Suggested Anti-OMA1 Antibody Titration: 0.2-1 μg/ml
    Positive Control: 721_B cell lysate
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96E52
Other Accession NM_145243, NP_660286
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Yeast, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Chicken, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 60 KDa
Additional Information
Gene ID 115209
Alias Symbol 2010001O09Rik, DAB1, FLJ33782, MPRP-1, YKR087C, ZMPOMA1
Other Names Metalloendopeptidase OMA1, mitochondrial, 3.4.24.-, Metalloprotease-related protein 1, MPRP-1, Overlapping with the m-AAA protease 1 homolog, OMA1, MPRP1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-OMA1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsOMA1 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name OMA1
Synonyms MPRP1
Function Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions.
Cellular Location Mitochondrion inner membrane; Multi-pass membrane protein
Tissue Location Widely expressed, with strong expression in the heart, skeletal muscle, kidney and liver
Research Areas
Citations (0)

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Bao Y.-C.,et al.DNA Res. 10:123-128(2003).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Head B.,et al.J. Cell Biol. 187:959-966(2009).

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$ 293.00
Cat# AI13463
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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