C1orf55 antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
---|---|
Primary Accession | Q6IQ49 |
Other Accession | NM_152608, NP_689821 |
Reactivity | Human, Mouse, Rat, Rabbit, Goat, Horse, Bovine, Guinea Pig, Dog |
Predicted | Human, Horse |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 50kDa |
Gene ID | 163859 |
---|---|
Alias Symbol | FLJ35382, RP4-671D7.1, dJ671D7.1, C1orf55 |
Other Names | Protein SDE2 homolog, SDE2, C1orf55 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-C1orf55 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | C1orf55 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SDE2 |
---|---|
Synonyms | C1orf55 |
Function | Inhibits translesion DNA synthesis by preventing monoubiquitination of PCNA, this is necessary to counteract damage due to ultraviolet light-induced replication stress (PubMed:27906959). SDE2 is cleaved following PCNA binding, and its complete degradation is necessary to allow S-phase progression following DNA damage (PubMed:27906959). |
Cellular Location | Nucleus. Cytoplasm |
Tissue Location | Ubiquitously expressed; enriched in brain, lung and liver. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Matsuoka S.,et al.Science 316:1160-1166(2007).
Cantin G.T.,et al.J. Proteome Res. 7:1346-1351(2008).
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.