|Other Accession||NM_005578, NP_005569|
|Reactivity||Human, Mouse, Rabbit, Horse, Bovine, Dog|
|Predicted||Human, Mouse, Rabbit, Horse, Bovine, Dog|
|Other Names||Lipoma-preferred partner, LIM domain-containing preferred translocation partner in lipoma, LPP|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-LPP antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||LPP antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a structural role at sites of cell adhesion in maintaining cell shape and motility. In addition to these structural functions, it may also be implicated in signaling events and activation of gene transcription. May be involved in signal transduction from cell adhesion sites to the nucleus allowing successful integration of signals arising from soluble factors and cell-cell adhesion sites. Also suggested to serve as a scaffold protein upon which distinct protein complexes are assembled in the cytoplasm and in the nucleus.|
|Cellular Location||Nucleus. Cytoplasm. Cell junction. Cell membrane. Note=Found in the nucleus, in the cytoplasm and at cell adhesion sites. Shuttles between the cytoplasm and the nucleus. It has been found in sites of cell adhesion such as cell-to-cell contact and focal adhesion which are membrane attachment sites of cells to the extracellular matrix. Mainly nuclear when fused with HMGA2/HMGIC and KMT2A/MLL1|
|Tissue Location||Expressed in a wide variety of tissues but no or very low expression in brain and peripheral leukocytes|
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Provided below are standard protocols that you may find useful for product applications.
Petit M.M.R.,et al.Genomics 36:118-129(1996).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Lemke I.,et al.Cytogenet. Cell Genet. 95:153-156(2001).
Petit M.M.,et al.Cancer Genet. Cytogenet. 106:18-23(1998).
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