|Other Accession||NM_008676, NP_032702|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Horse, Bovine, Dog|
|Other Names||Next to BRCA1 gene 1 protein, Membrane component chromosome 17 surface marker 2 homolog, Neighbor of BRCA1 gene 1 protein, Nbr1, M17s2|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Nbr1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Nbr1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts probably as a receptor for selective autophagosomal degradation of ubiquitinated targets.|
|Cellular Location||Cytoplasm. Cytoplasmic vesicle, autophagosome. Lysosome Cytoplasm, myofibril, sarcomere, M line. Note=In cardiac muscles localizes to the sarcomeric M line. Is targeted to lysosomes for degradation.|
|Tissue Location||Expressed in brain.|
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Chambers J.A.,et al.Genomics 38:305-313(1996).
Dimitrov S.,et al.Gene 262:89-98(2001).
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