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STAG3 antibody - middle region

Rabbit Polyclonal Antibody

  • WB - STAG3 antibody - middle region AI13597

    WB Suggested Anti-STAG3 Antibody Titration: 0.2-1 μg/ml
    Positive Control: 721_B cell lysate
    STAG3 is supported by BioGPS gene expression data to be expressed in 721_B
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UJ98
Other Accession NM_012447, NP_036579
Reactivity Human
Predicted Human
Host Rabbit
Clonality Polyclonal
Calculated MW 135kDa
Additional Information
Gene ID 10734
Other Names Cohesin subunit SA-3, SCC3 homolog 3, Stromal antigen 3, Stromalin-3, STAG3
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-STAG3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsSTAG3 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name STAG3
Function Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis- specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00750, ECO:0000269|PubMed:12034751}. Chromosome. Chromosome, centromere. Note=Associates with chromatin. In prophase I stage of meiosis, it is found along the axial elements of synaptonemal complexes. In late-pachytene-diplotene, the bulk of protein dissociates from the chromosome arms probably because of phosphorylation by PLK1, except at centromeres, where cohesin complexes remain. It however remains chromatin associated at the centromeres up to metaphase I. During anaphase I, it probably dissociates from centromeres, allowing chromosomes segregation
Tissue Location Testis specific.
Research Areas
Citations (0)

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Pezzi N.,et al.FASEB J. 14:581-592(2000).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 424:157-164(2003).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 293.00
Cat# AI13597
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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