C17orf81 antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q8TE02 |
Other Accession | NM_015362, NP_056177 |
Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Dog |
Predicted | Human, Rabbit, Horse, Bovine, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 35kDa |
Gene ID | 23587 |
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Alias Symbol | DERP6, HSPC002, MST071, MSTP071, C17orf81 |
Other Names | Elongator complex protein 5, Dermal papilla-derived protein 6, S-phase 2 protein, ELP5, C17orf81, DERP6 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-C17orf81 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | C17orf81 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ELP5 {ECO:0000303|PubMed:22854966, ECO:0000312|HGNC:HGNC:30617} |
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Function | Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (PubMed:29332244). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (PubMed:29332244). Involved in cell migration (By similarity). |
Cellular Location | Nucleus. Cytoplasm |
Tissue Location | Ubiquitously expressed with high levels in heart, brain, liver, skeletal muscle and testis |
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Provided below are standard protocols that you may find useful for product applications.
References
Yuan J.,et al.Mol. Biol. Rep. 33:151-158(2006).
Ikeda A.,et al.Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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