|Other Accession||NM_015362, NP_056177|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Dog|
|Predicted||Human, Rabbit, Horse, Bovine, Dog|
|Alias Symbol||DERP6, HSPC002, MST071, MSTP071, C17orf81|
|Other Names||Elongator complex protein 5, Dermal papilla-derived protein 6, S-phase 2 protein, ELP5, C17orf81, DERP6|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-C17orf81 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||C17orf81 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Involved in cell migration (By similarity). May be involved in TP53-mediated transcriptional regulation.|
|Cellular Location||Nucleus. Cytoplasm.|
|Tissue Location||Ubiquitously expressed with high levels in heart, brain, liver, skeletal muscle and testis|
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Provided below are standard protocols that you may find useful for product applications.
Yuan J.,et al.Mol. Biol. Rep. 33:151-158(2006).
Ikeda A.,et al.Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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