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HOOK2 Antibody - middle region

Rabbit Polyclonal Antibody

  • WB - HOOK2 Antibody - middle region AI13716

    Host: Rabbit
    Target Name: HOOK2
    Sample Tissue: Fetal Liver lysates
    Antibody Dilution: 1.0μg/ml
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96ED9
Reactivity Human
Predicted Human, Mouse, Rat, Pig, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 79kDa
Additional Information
Gene ID 29911
Alias Symbol HOOK2,
Other Names Protein Hook homolog 2, h-hook2, hHK2, HOOK2
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 &mu, l of distilled water. Final Anti-HOOK2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
PrecautionsHOOK2 Antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HOOK2
Function Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Contributes to the establishment and maintenance of centrosome function. May function in the positioning or formation of aggresomes, which are pericentriolar accumulations of misfolded proteins, proteasomes and chaperones.
Cellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Cytoplasm, cytoskeleton Note=Colocalizes with aggresomes, which are aggregates of misfolded proteins, at the centrosome. Also localizes to punctate cytoplasmic foci which do not appear to overlap with early or late endosomes, the endoplasmic reticulum, the Golgi complex, multivesicular bodies (MVBs), lysosomes, or mitochondria. Often found in close association with microtubules
Citations (0)

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Kraemer H.,et al.Genetics 151:675-684(1999).
Grimwood J.,et al.Nature 428:529-535(2004).
Walenta J.H.,et al.J. Cell Biol. 152:923-934(2001).
Szebenyi G.,et al.BMC Cell Biol. 8:19-19(2007).
Szebenyi G.,et al.Traffic 8:32-46(2007).

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$ 293.00
Cat# AI13716
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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