|Other Accession||NM_014012, NP_054731|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Sheep, Horse, Yeast, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Sheep, Bovine, Guinea Pig, Dog|
|Alias Symbol||GD:REM, GES, MGC48669, REM|
|Other Names||GTP-binding protein REM 1, GTPase-regulating endothelial cell sprouting, Rad and Gem-like GTP-binding protein 1, REM1, GES, REM|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-REM1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||REM1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Promotes endothelial cell sprouting and actin cytoskeletal reorganization. May be involved in angiogenesis. May function in Ca(2+) signaling.|
|Tissue Location||Most highly expressed in the endothelial lining of the blood vessels in uterus and heart. Lower levels found in spleen, lymph node, kidney and testis. Also found in cells with secretory function such as the islets of Langerhans, lobule/duct epithelium in the breast, bile duct epithelium in the liver, surface epithelium in the endometrial glands of the uterus, colon mucosa and acinar cells in the pancreas and the prostate|
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Provided below are standard protocols that you may find useful for product applications.
Finlin B.S.,et al.Submitted (AUG-1998) to the EMBL/GenBank/DDBJ databases.
Pan J.Y.,et al.J. Cell Biol. 149:1107-1116(2000).
Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Deloukas P.,et al.Nature 414:865-871(2001).
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