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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Dkk2 antibody - middle region   

Dkk2 antibody - middle region

Rabbit Polyclonal Antibody

  • WB - Dkk2 antibody - middle region AI13730

    WB Suggested Anti-Dkk2 Antibody Titration: 1.0 μg/ml
    Positive Control: Mouse Pancreas
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9QYZ8
Other Accession NM_020265, NP_064661
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Pig, Chicken, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 28kDa
Additional Information
Gene ID 56811
Other Names Dickkopf-related protein 2, Dickkopf-2, Dkk-2, mDkk-2, Dkk2
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Dkk2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsDkk2 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Dkk2
Function Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
Cellular Location Secreted.
Research Areas
Citations (0)

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Monaghan P.A.,et al.Mech. Dev. 87:45-56(1999).
Carninci P.,et al.Science 309:1559-1563(2005).
Church D.M.,et al.PLoS Biol. 7:E1000112-E1000112(2009).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Niehrs C.,et al.Oncogene 25:7469-7481(2006).

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$ 293.00
Cat# AI13730
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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