|Other Accession||NM_014931, NP_055746|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Alias Symbol||KIAA1115, MGC138185, MGC142003, PP6R1, SAP190, SAPS1|
|Other Names||Serine/threonine-protein phosphatase 6 regulatory subunit 1, SAPS domain family member 1, PPP6R1, KIAA1115, PP6R1, SAPS1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-PPP6R1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||PPP6R1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||KIAA1115, PP6R1, SAPS1|
|Function||Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6- mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha.|
|Tissue Location||Ubiquitous with higher expression in testis.|
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Provided below are standard protocols that you may find useful for product applications.
Kikuno R.,et al.DNA Res. 6:197-205(1999).
Ohara O.,et al.Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.
Olsen J.V.,et al.Cell 127:635-648(2006).
Stefansson B.,et al.J. Biol. Chem. 281:22624-22634(2006).
Stefansson B.,et al.Biochemistry 47:1442-1451(2008).
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