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Agtpbp1 Antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - Agtpbp1 Antibody - C-terminal region AI13761

    Host: Rabbit
    Target Name: Agtpbp1
    Sample Tissue: Mouse Testis lysates
    Antibody Dilution: 1.0μg/ml
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q641K1
Other Accession NM_023328, NP_075817
Reactivity Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 128kDa
Additional Information
Gene ID 67269
Alias Symbol 1700020N17Rik, 2310001G17Rik, 2900054O13Rik, 4930445M19Rik, 5730402G09Rik, BB114605, CCP1, Nna1, mKIAA1035, nmf243, pcd
Other Names Cytosolic carboxypeptidase 1, 3.4.17.-, ATP/GTP-binding protein 1, Nervous system nuclear protein induced by axotomy protein 1, Agtpbp1, Ccp1, Nna1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Agtpbp1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsAgtpbp1 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Agtpbp1
Synonyms Ccp1, Nna1
Function Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5. Deglutamylation plays a key role in cerebellar Purkinje cell differentiation, accumulation of tubulin polyglutamylation causing neurodegeneration.
Cellular Location Cytoplasm {ECO:0000250|UniProtKB:Q9UPW5}. Cytoplasm, cytosol. Nucleus. Mitochondrion. Note=Localizes in both the cytoplasm and nuclei of interphase and dividing cells {ECO:0000250|UniProtKB:Q9UPW5}
Tissue Location Widely expressed. Highly expressed in the cerebellum and cortex of adult mouse brain. Expressed at similar levels in both the cerebellum and the cortex throughout all developmental stages. Also expressed in sciatic nerve transection, spinal motor neurons undergoing axon regeneration, testis, heart and in developing brain. Expression in cranial motor nuclei is the same as that observed in uninjured primary motor neurons Expression is prevalent in sensory neurons and hippocampal CA3 neurons in addition to regenerating motor neurons
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$ 293.00
Cat# AI13761
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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