|Other Accession||NM_015649, NP_056464|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Other Names||Interferon regulatory factor 2-binding protein 1, IRF-2-binding protein 1, IRF-2BP1, Probable E3 ubiquitin-protein ligase IRF2BP1, 6.3.2.-, IRF2BP1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-IRF2BP1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||IRF2BP1 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts as a transcriptional corepressor in a IRF2- dependent manner; this repression is not mediated by histone deacetylase activities. May act as an E3 ligase towards JDP2, enhancing its polyubiquitination. Represses ATF2-dependent transcriptional activation.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Childs K.S.,et al.Nucleic Acids Res. 31:3016-3026(2003).
Totoki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Olsen J.V.,et al.Cell 127:635-648(2006).
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