|Other Accession||NM_178566, NP_848661|
|Reactivity||Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Rat, Rabbit, Dog|
|Alias Symbol||DNZ1, DHHC-21, HSPC097, 9130404H11Rik|
|Other Names||Probable palmitoyltransferase ZDHHC21, 220.127.116.11, Zinc finger DHHC domain-containing protein 21, DHHC-21, ZDHHC21|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-ZDHHC21 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||ZDHHC21 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Palmitoylates sex steroid hormone receptors, including ESR1, PGR and AR, thereby regulating their targeting to the plasma membrane. This affects rapid intracellular signaling by sex hormones via ERK and AKT kinases and the generation of cAMP, but does not affect that mediated by their nuclear receptor (By similarity).|
|Cellular Location||Membrane; Multi-pass membrane protein. Golgi apparatus|
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