|Other Accession||NM_026720, NP_080996|
|Reactivity||Human, Mouse, Rat, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Mouse, Rat, Horse, Bovine, Guinea Pig, Dog|
|Alias Symbol||0710001P18Rik, AI430801|
|Other Names||Ankyrin repeat domain-containing protein 13D, Ankrd13d|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Ankrd13d antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Ankrd13d antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand- activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane (By similarity).|
|Cellular Location||Cell membrane. Late endosome. Note=Interaction with EGFR may enhance association with the cell membrane.|
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Church D.M.,et al.PLoS Biol. 7:E1000112-E1000112(2009).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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