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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Rap1a Antibody - middle region   

Rap1a Antibody - middle region

Rabbit Polyclonal Antibody

  • WB - Rap1a Antibody - middle region AI13915

    Host: Rabbit
    Target Name: Rap1a
    Sample Tissue: Mouse Testis lysates
    Antibody Dilution: 1.0μg/ml
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P62835
Other Accession NM_145541, NP_663516
Reactivity Human, Mouse, Rat, Rabbit, Pig, Goat, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Goat, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 20kDa
Additional Information
Gene ID 109905
Alias Symbol AI848598, G-22K, Krev-1, Rap1
Other Names Ras-related protein Rap-1A, Ras-related protein Krev-1, Rap1a, Krev-1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Rap1a antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsRap1a Antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Rap1a
Synonyms Krev-1
Function Induces morphological reversion of a cell line transformed by a Ras oncogene. Counteracts the mitogenic function of Ras, at least partly because it can interact with Ras GAPs and RAF in a competitive manner. Together with ITGB1BP1, regulates KRIT1 localization to microtubules and membranes (By similarity). Plays a role in nerve growth factor (NGF)-induced neurite outgrowth. Plays a role in the regulation of embryonic blood vessel formation. Involved in the establishment of basal endothelial barrier function. May be involved in the regulation of the vascular endothelial growth factor receptor KDR expression at endothelial cell-cell junctions.
Cellular Location Cell membrane; Lipid-anchor. Cell junction Cytoplasm. Cytoplasm, perinuclear region. Early endosome. Late endosome. Note=Recruited from early endosome to late endosome compartment after nerve growth factor (NGF) stimulation Colocalized with RAPGEF2 in the perinuclear region (By similarity). Localized with RAPGEF2 at cell-cell junctions
Research Areas
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Kanemura H.,et al.Biochem. Biophys. Res. Commun. 387:754-759(2009).

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$ 293.00
Cat# AI13915
(40 western blots)
Availability: 2-3 days
Bulk Size
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