|Other Accession||NM_001040446, NP_001035536|
|Reactivity||Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Alias Symbol||3-PAP, PIP3AP|
|Other Names||Myotubularin-related protein 12, Phosphatidylinositol 3 phosphate 3-phosphatase adapter subunit, 3-PAP, 3-phosphatase adapter protein, MTMR12, KIAA1682, PIP3AP|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-MTMR12 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||MTMR12 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalytically inactive phosphatase that plays a role as an adapter for the phosphatase myotubularin to regulate myotubularin intracellular location.|
|Cellular Location||Cytoplasm. Note=Localizes to punctate vesicles when associated with MTM1|
|Tissue Location||Ubiquitous with prominent expression in brain, heart, kidney, placenta, and lung.|
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Provided below are standard protocols that you may find useful for product applications.
Nandurkar H.H.,et al.Proc. Natl. Acad. Sci. U.S.A. 98:9499-9504(2001).
Nagase T.,et al.DNA Res. 7:347-355(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Nandurkar H.H.,et al.Proc. Natl. Acad. Sci. U.S.A. 100:8660-8665(2003).
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