|Other Accession||NM_002536, NP_002527|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Other Names||TBC1 domain family member 25, TBC1D25, OATL1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 &mu, l of distilled water. Final Anti-TBC1D25 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||TBC1D25 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts as a GTPase-activating protein specific for RAB33B. Involved in the regulation of autophagosome maturation, the process in which autophagosomes fuse with endosomes and lysosomes.|
|Cellular Location||Cytoplasm. Cytoplasmic vesicle, autophagosome Note=It is dispersed in the cytoplasm under nutrient-rich conditions. Localizes at autophagosomes under cell starving conditions|
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Provided below are standard protocols that you may find useful for product applications.
Ross M.T.,et al.Nature 434:325-337(2005).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Mayya V.,et al.Sci. Signal. 2:RA46-RA46(2009).
Olsen J.V.,et al.Sci. Signal. 3:RA3-RA3(2010).
Itoh T.,et al.J. Cell Biol. 192:839-853(2011).
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