TBC1D25 Antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q3MII6 |
Other Accession | NM_002536, NP_002527 |
Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
Predicted | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 75kDa |
Gene ID | 4943 |
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Alias Symbol | TBC1D25 |
Other Names | TBC1 domain family member 25, TBC1D25, OATL1 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 &mu, l of distilled water. Final Anti-TBC1D25 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |
Precautions | TBC1D25 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TBC1D25 |
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Synonyms | OATL1 |
Function | Acts as a GTPase-activating protein specific for RAB33B. Involved in the regulation of autophagosome maturation, the process in which autophagosomes fuse with endosomes and lysosomes. |
Cellular Location | Cytoplasm. Cytoplasmic vesicle, autophagosome Note=It is dispersed in the cytoplasm under nutrient-rich conditions Localizes at autophagosomes under cell starving conditions |
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Provided below are standard protocols that you may find useful for product applications.
References
Ross M.T.,et al.Nature 434:325-337(2005).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Mayya V.,et al.Sci. Signal. 2:RA46-RA46(2009).
Olsen J.V.,et al.Sci. Signal. 3:RA3-RA3(2010).
Itoh T.,et al.J. Cell Biol. 192:839-853(2011).
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