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RAB1A antibody - middle region

Rabbit Polyclonal Antibody

  • IHC - RAB1A antibody - middle region AI13962
    Rabbit Anti-RAB1A Antibody
    Catalog Number: AI13962
    Formalin Fixed Paraffin Embedded Tissue: Human Bronchial Epithelial Tissue Observed Staining: Cytoplasmic in excellent staining
    Primary Antibody
    Concentration: 1:100
    Secondary Antibody: Donkey anti-Rabbit-Cy3
    Secondary Antibody
    Concentration: 1:200
    Magnification: 20X
    Exposure Time: 0.5 - 2.0 sec
  • WB - RAB1A antibody - middle region AI13962
    Sample Type: 1. Human Cervical Cancer cell lysate
    (15ug) 2. Monkey Fibroblast cell lysate
    (15ug) 3. Human Cervical Cancer Cell transfected with Rab1A-GFP (15ug) Primary Dilution: 1:1000
    Secondary Antibody: goat anti-Rabbit Secondary Dilution: 1:40,000 Image
    Submitted by: Dr. Jakob Szwedo, Dr. Lupashin's Lab University of Arkansas for Medical SciencesSee Customer Feedback tab for detailed information.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P62820
Other Accession NM_004161, NP_004152
Reactivity Human, Mouse, Rat, Rabbit, Pig, Goat, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Chicken, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 23kDa
Additional Information
Gene ID 5861
Alias Symbol DKFZP564B163, RAB1, YPT1
Other Names Ras-related protein Rab-1A, YPT1-related protein, RAB1A, RAB1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-RAB1A antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsRAB1A antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RAB1A
Synonyms RAB1
Function The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secretion. Regulates the level of CASR present at the cell membrane. Plays a role in cell adhesion and cell migration, via its role in protein trafficking. Plays a role in autophagosome assembly and cellular defense reactions against pathogenic bacteria. Plays a role in microtubule-dependent protein transport by early endosomes and in anterograde melanosome transport.
Cellular Location Golgi apparatus. Endoplasmic reticulum. Early endosome. Cytoplasm, cytosol. Membrane. Melanosome. Note=Alternates between membrane-associated and cytosolic forms
Research Areas
Citations (0)

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Zahraoui A.,et al.J. Biol. Chem. 264:12394-12401(1989).
Wiemann S.,et al.Genome Res. 11:422-435(2001).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Puhl H.L. III,et al.Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.

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$ 293.00
Cat# AI13962
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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