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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   RP2 antibody - middle region   

RP2 antibody - middle region

Rabbit Polyclonal Antibody

  • IHC - RP2 antibody - middle region AI13992
    Immunohistochemistry with Brain, cerebellum tissue at an antibody concentration of 5μg/ml using anti-RP2 antibody (AI13992)
  • WB - RP2 antibody - middle region AI13992

    WB Suggested Anti-RP2 Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:1562500
    Positive Control: Human Muscle
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O75695
Other Accession NM_006003, NP_008846
Reactivity Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rabbit, Horse, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 40kDa
Additional Information
Gene ID 6102
Alias Symbol KIAA0215, TBCCD2, XRP2, NME10, DELXp11.3
Other Names Protein XRP2, RP2
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-RP2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsRP2 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RP2
Function Acts as a GTPase-activating protein (GAP) involved in trafficking between the Golgi and the ciliary membrane. Involved in localization of proteins, such as NPHP3, to the cilium membrane by inducing hydrolysis of GTP ARL3, leading to the release of UNC119 (or UNC119B). Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization. Acts as guanine nucleotide dissociation inhibitor towards ADP-ribosylation factor-like proteins.
Cellular Location Cell membrane; Lipid-anchor; Cytoplasmic side. Cell projection, cilium. Note=Detected predominantly to the plasma membrane of rod and cone photoreceptors. Not detected in the nucleus
Tissue Location Ubiquitous. Expressed in the rod and cone photoreceptors, extending from the tips of the outer segment (OS) through the inner segment (IS) and outer nuclear layer (ONL) and into the synaptic terminals of the outer plexiform layer (ONL) Also detected in the bipolar, horizontal and amacrine cells in the inner nuclear layer (INL), extending to the inner plexiform layer (IPL) and though the ganglion cell layer (GCL) and into the nerve fiber layer (NFL) (at protein level)
Research Areas
Citations (0)

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Schwahn U.,et al.Nat. Genet. 19:327-332(1998).
Ross M.T.,et al.Nature 434:325-337(2005).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
Chapple J.P.,et al.Hum. Mol. Genet. 9:1919-1926(2000).
Bartolini F.,et al.J. Biol. Chem. 277:14629-14634(2002).

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$ 293.00
Cat# AI13992
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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