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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   TPRKB antibody - middle region   

TPRKB antibody - middle region

Rabbit Polyclonal Antibody

  • WB - TPRKB antibody - middle region AI14008

    WB Suggested Anti-TPRKB Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:62500
    Positive Control: THP-1 cell lysate
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y3C4
Other Accession NM_016058, NP_057142
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Yeast, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Pig, Chicken, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 20kDa
Additional Information
Gene ID 51002
Alias Symbol CGI-121
Other Names EKC/KEOPS complex subunit TPRKB, PRPK-binding protein, TP53RK-binding protein, TPRKB
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-TPRKB antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsTPRKB antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t(6)A activity of the complex. TPRKB is not required for tRNA modification (By similarity).
Cellular Location Cytoplasm. Nucleus.
Tissue Location Widely expressed.
Research Areas
Citations (0)

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Miyoshi A.,et al.Biochem. Biophys. Res. Commun. 303:399-405(2003).
Mao Y.M.,et al.Submitted (APR-1998) to the EMBL/GenBank/DDBJ databases.
Lai C.-H.,et al.Genome Res. 10:703-713(2000).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Oppermann F.S.,et al.Mol. Cell. Proteomics 8:1751-1764(2009).

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$ 293.00
Cat# AI14008
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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