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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   HECA antibody - middle region   

HECA antibody - middle region

Rabbit Polyclonal Antibody

     
  • WB - HECA antibody - middle region AI14017

    WB Suggested Anti-HECA Antibody Titration: 0.2-1 μg/ml
    Positive Control: PANC1 cell lysate
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q9UBI9
Other Accession NM_016217, NP_057301
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Mouse, Rat, Rabbit, Pig, Chicken, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 59kDa
Additional Information
Alias Symbol HDC, HDCL, HHDC, dJ225E12.1
Other Names Headcase protein homolog, hHDC, HECA, HDC
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-HECA antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsHECA antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HECA
Synonyms HDC
Function May play an important role in some human cancers. May be part of the regulatory mechanism in the development of epithelial tube networks such as the circulatory system and lungs.
Tissue Location Expressed in all tissues examined. Highest levels are in the spleen, thymus, peripheral blood and heart Lowest in the kidney and pancreas. EMBL; AB033496; BAA85333.1; -; Genomic_DNA EMBL; AB033492; BAA85322.1; -; mRNA EMBL; AL031772; CAB94782.1; -; Genomic_DNA EMBL; BC070068; AAH70068.1; -; mRNA CCDS; CCDS5194.1; - RefSeq; NP_057301.1; NM_016217.2 UniGene; Hs.197644; - ProteinModelPortal; Q9UBI9; - SMR; Q9UBI9; - BioGrid; 119682; 1 STRING; 9606.ENSP00000356630; - iPTMnet; Q9UBI9; - PhosphoSitePlus; Q9UBI9; - BioMuta; HECA; - DMDM; 44887986; - EPD; Q9UBI9; - MaxQB; Q9UBI9; - PaxDb; Q9UBI9; - PeptideAtlas; Q9UBI9; - PRIDE; Q9UBI9; - Ensembl; ENST00000367658; ENSP00000356630; ENSG00000112406 GeneID; 51696; - KEGG; hsa:51696; - UCSC; uc003qin.4; human CTD; 51696; - DisGeNET; 51696; - GeneCards; HECA; - HGNC; HGNC:21041; HECA HPA; HPA042313; - MIM; 607977; gene neXtProt; NX_Q9UBI9; - OpenTargets; ENSG00000112406; - PharmGKB; PA134977625; - eggNOG; KOG3816; Eukaryota eggNOG; ENOG410XREE; LUCA GeneTree; ENSGT00500000044928; - HOGENOM; HOG000112873; - HOVERGEN; HBG049012; - InParanoid; Q9UBI9; - OMA; MEDDAQM; - OrthoDB; EOG091G054P; - PhylomeDB; Q9UBI9; - TreeFam; TF315512; - BioCyc; ZFISH:ENSG00000112406-MONOMER; - ChiTaRS; HECA; human GenomeRNAi; 51696; - PRO; PR:Q9UBI9; - Proteomes; UP000005640; Chromosome 6 Bgee; ENSG00000112406; - CleanEx; HS_HDC; - CleanEx; HS_HECA; - Genevisible; Q9UBI9; HS GO; GO:0005737; C:cytoplasm; IDA:HGNC GO; GO:0016020; C:membrane; IDA:UniProtKB GO; GO:0005634; C:nucleus; IDA:HGNC GO; GO:0045930; P:negative regulation of mitotic cell cycle; IDA:HGNC GO; GO:0030323; P:respiratory tube development; NAS:UniProtKB InterPro; IPR026066; Headcase InterPro; IPR031947; Headcase_mid PANTHER; PTHR13425; PTHR13425; 1 Pfam; PF16002; Headcase; 1 Pfam; PF15353; HECA; 1 1: Evidence at protein level; Complete proteome; Developmental protein; Phosphoprotein; Reference proteome CHAIN 1 543 Headcase protein homolog /FTId=PRO_0000083934 COMPBIAS 9 95 Ala/Gly-rich MOD_RES 264 264 Phosphoserine MOD_RES 268 268 Phosphoserine SEQUENCE 543 AA; 58837 MW; A161B7F4C57EF0D1 CRC64; MPNPKNSKGG RKNKRANSSG DEQENGAGAL AAAGAAGAAA GGALAAAAGC GAAAAGAPGA GGAAGAGGAG TGAANAAAAA GAAAAGDAKN EAPCATPLIC SFGRPVDLEK DDYQKVVCNN EHCPCSTWMH LQCFYEWESS ILVQFNCIGR ARSWNEKQCR QNMWTKKGYD LAFRFCSCRC GQGHLKKDTD WYQVKRMQDE KKKKSGSEKN TGRPPGEAAE EAKKCRPPNK PQKGPSHDLP RRHSMDRQNS QEKAVGAAAY GARSPGGSPG QSPPTGYSIL SPAHFSGPRS SRYLGEFLKN AIHLEPHKKA MAGGHVFRNA HFDYSPAGLA VHRGGHFDTP VQFLRRLDLS ELLTHIPRHK LNTFHVRMED DAQVGQGEDL RKFILAALSA SHRNVVNCAL CHRALPVFEQ FPLVDGTLFL SPSRHDEIEY DVPCHLQGRL MHLYAVCVDC LEGVHKIICI KCKSRWDGSW HQLGTMYTYD ILAASPCCQA RLNCKHCGKP VIDVRIGMQY FSEYSNVQQC PHCGNLDYHF VKPFSSFKVL EAY
Research Areas
Citations (0)

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References

Makino N.,et al.DNA Seq. 11:547-553(2001).
Mungall A.J.,et al.Nature 425:805-811(2003).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Mayya V.,et al.Sci. Signal. 2:RA46-RA46(2009).

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$ 293.00
Cat# AI14017
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