|Other Accession||NM_016246, NP_057330|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Dog|
|Predicted||Mouse, Rat, Rabbit, Pig, Dog|
|Alias Symbol||DHRS10, retSDR3, SDR47C1|
|Other Names||17-beta-hydroxysteroid dehydrogenase 14, 17-beta-HSD 14, 1.1.1.-, 17-beta-hydroxysteroid dehydrogenase DHRS10, Dehydrogenase/reductase SDR family member 10, Retinal short-chain dehydrogenase/reductase retSDR3, HSD17B14, DHRS10, SDR3|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-HSD17B14 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||HSD17B14 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||DHRS10, SDR3, SDR47C1|
|Function||Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3- beta,17-beta-diol (in vitro).|
|Tissue Location||Highly expressed in brain, placenta, liver and kidney.|
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Provided below are standard protocols that you may find useful for product applications.
Haeseleer F.,et al.Methods Enzymol. 316:372-383(2000).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Lukacik P.,et al.Biochem. J. 402:419-427(2007).
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