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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Pi4k2b antibody - N-terminal region   

Pi4k2b antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - Pi4k2b antibody - N-terminal region AI14075

    WB Suggested Anti-Pi4k2b Antibody Titration: 1.0 μg/ml
    Positive Control: Mouse Liver
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8CBQ5
Other Accession NM_025951, NP_080227
Reactivity Human, Mouse, Rat, Rabbit, Horse, Yeast, Bovine, Guinea Pig, Dog
Predicted Human, Rabbit, Chicken, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 52kDa
Additional Information
Gene ID 67073
Alias Symbol 2610042N09Rik, 4933409G22Rik
Other Names Phosphatidylinositol 4-kinase type 2-beta,, Phosphatidylinositol 4-kinase type II-beta, Pi4k2b
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Pi4k2b antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsPi4k2b antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Pi4k2b
Function Together with PI4K2A and the type III PI4Ks (PIK4CA and PIK4CB) it contributes to the overall PI4-kinase activity of the cell. This contribution may be especially significant in plasma membrane, endosomal and Golgi compartments. The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3). Contributes to the production of InsP3 in stimulated cells and is likely to be involved in the regulation of vesicular trafficking (By similarity).
Cellular Location Cytoplasm. Membrane. Note=Mostly cytoplasmic but also found associated with the plasma membrane, the Golgi and endosomes. Compared to PI4K2A, a larger fraction of PI4K2B is cytosolic due to a smaller extent of palmitoylation. Translocates to membranes where it is recruited by PDGF stimulation by a Rac-GTP-dependent mechanism (By similarity).
Research Areas
Citations (0)

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Hong W.,et al.Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases.
Li W.,et al.Submitted (SEP-2002) to the EMBL/GenBank/DDBJ databases.
Carninci P.,et al.Science 309:1559-1563(2005).
Trost M.,et al.Immunity 30:143-154(2009).

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$ 293.00
Cat# AI14075
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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