EXOC6 antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q8TAG9 |
Other Accession | NM_019053, NP_061926 |
Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
Predicted | Human, Mouse, Rat, Rabbit, Pig, Chicken, Horse, Bovine, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 94kDa |
Gene ID | 54536 |
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Alias Symbol | DKFZp761I2124, EXOC6A, FLJ1125, FLJ11251, MGC33397, SEC15L, SEC15L1, SEC15L3, Sec15p, SEC15 |
Other Names | Exocyst complex component 6, Exocyst complex component Sec15A, SEC15-like protein 1, EXOC6, SEC15A, SEC15L, SEC15L1 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-EXOC6 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | EXOC6 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | EXOC6 |
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Synonyms | SEC15A, SEC15L, SEC15L1 |
Function | Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Together with RAB11A, RAB3IP, RAB8A, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis (By similarity). |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:O54923}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:O54923}. Cell projection, growth cone {ECO:0000250|UniProtKB:O54923}. Midbody, Midbody ring. Note=Perinuclear in undifferentiated cells. Redistributes to growing neurites and growth cones during neuronal differentiation. Colocalizes with CNTRL/centriolin at the midbody ring (PubMed:16213214) {ECO:0000250|UniProtKB:O54923, ECO:0000269|PubMed:16213214} |
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Provided below are standard protocols that you may find useful for product applications.
References
Deloukas P.,et al.Nature 429:375-381(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Li C.,et al.Submitted (DEC-1999) to the EMBL/GenBank/DDBJ databases.
Gromley A.,et al.Cell 123:75-87(2005).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
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