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MFN1 antibody - middle region

Rabbit Polyclonal Antibody

  • WB - MFN1 antibody - middle region AI14182

    WB Suggested Anti-MFN1 Antibody Titration: 0.2-1 μg/ml
    Positive Control: Human Placenta
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8R4Z9
Other Accession NM_033540, NP_284941
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Dog
Predicted Human, Mouse, Rat, Rabbit, Chicken, Horse, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 84 KDa
Additional Information
Gene ID 192647
Alias Symbol DKFZp762F247, FLJ20693, MGC41806, hfzo1, hfzo2
Other Names Mitofusin-1, 3.6.5.-, Mitochondrial transmembrane GTPase FZO1B, Transmembrane GTPase MFN1, Mfn1, Fzo1b
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-MFN1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsMFN1 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Mfn1
Synonyms Fzo1b
Function Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks.
Cellular Location Mitochondrion outer membrane; Multi-pass membrane protein
Tissue Location Ubiquitous. In brain, it is expressed at weaker level than MFN2, while it is expressed at a higher level than MFN2 in heart and testis. Expressed at high level in elongating spermatids of seminiferous tubules
Citations (0)

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Eura Y.,et al.J. Biochem. 134:333-344(2003).
Ishihara N.,et al.Biochem. Biophys. Res. Commun. 301:891-898(2003).
Honda S.,et al.Biochem. Biophys. Res. Commun. 311:424-432(2003).
Eura Y.,et al.J. Cell Sci. 119:4913-4925(2006).

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$ 293.00
Cat# AI14182
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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