Zar1l Antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | C3VD30 |
Other Accession | NM_001159693, NP_001153165 |
Reactivity | Mouse |
Predicted | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 32kDa |
Gene ID | 545824 |
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Alias Symbol | XM_359419 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Zar1l antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | Zar1l Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Zar1l {ECO:0000303|PubMed:20014101, ECO:0000312|MGI:MGI:3690051} |
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Function | mRNA-binding protein required for maternal mRNA storage, translation and degradation during oocyte maturation (PubMed:31598710). Probably promotes formation of some phase-separated membraneless compartment that stores maternal mRNAs in oocytes: acts by undergoing liquid-liquid phase separation upon binding to maternal mRNAs (By similarity). Binds to the 3'-UTR of maternal mRNAs, inhibiting their translation (PubMed:31598710). |
Cellular Location | Cytoplasm, Cytoplasmic ribonucleoprotein granule |
Tissue Location | Expressed in oocytes and zygotes (PubMed:20014101, PubMed:31598710). Predominantly expressed in maturing oocytes before maternal-to-zygotic transition (MZT) (PubMed:31598710). Less abundant than Zar1 (PubMed:31598710). |
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