|Other Accession||NM_144939, NP_659188|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Alias Symbol||4930417B13Rik, AI449674, Frs2beta, MGC25496, Snt2|
|Other Names||Fibroblast growth factor receptor substrate 3, FGFR substrate 3, FRS2-beta, Frs3, Frs2b|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Frs3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Frs3 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.|
|Cellular Location||Membrane; Lipid-anchor.|
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Provided below are standard protocols that you may find useful for product applications.
Zhou L.,et al.Mol. Biol. Rep. 30:15-25(2003).
Ong S.-H.,et al.Mol. Cell. Biol. 20:979-989(2000).
Avery A.W.,et al.Cell. Signal. 19:177-184(2007).
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