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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Cxxc5 Antibody - N-terminal region   

Cxxc5 Antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - Cxxc5 Antibody - N-terminal region AI14325

    Host: Rabbit
    Target Name: Cxxc5
    Sample Tissue: Mouse Heart lysates
    Antibody Dilution: 1.0μg/ml
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q91WA4
Other Accession NM_133687, NP_598448
Reactivity Human, Mouse, Rat, Horse, Guinea Pig
Predicted Human, Mouse, Rat, Pig, Horse, Guinea Pig
Host Rabbit
Clonality Polyclonal
Calculated MW 33kDa
Additional Information
Gene ID 67393
Alias Symbol 4930415K17Rik
Other Names CXXC-type zinc finger protein 5, Cxxc5
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Cxxc5 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsCxxc5 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Cxxc5
Function May indirectly participate in activation of the NF- kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells. Required for DNA damage-induced ATM phosphorylation, p53 activation and cell cycle arrest. Involved in myelopoiesis (By similarity). Binds to the oxygen responsive element of COX4I2 and represses its transcription under hypoxia conditions (4% oxygen), as well as normoxia conditions (20% oxygen). May repress COX4I2 transactivation induced by CHCHD2 and RBPJ (By similarity).
Cellular Location Nucleus. Cytoplasm. Note=Colocalizes with DVL1 in large bodies localized just outside the nuclear membrane.
Research Areas
Citations (0)

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Carninci P.,et al.Science 309:1559-1563(2005).
Andersson T.,et al.J. Biol. Chem. 284:3672-3681(2009).

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$ 293.00
Cat# AI14325
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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