|Other Accession||NM_021513, NP_067488|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Rat, Rabbit, Pig, Horse, Guinea Pig, Dog|
|Alias Symbol||2810036E22Rik, AB041579, CTG-B43a, CTG-B45d, Ronin|
|Other Names||THAP domain-containing protein 11, Ronin, Thap11|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Thap11 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Thap11 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers.|
|Cellular Location||Nucleus. Cytoplasm. Note=May be regulated by shuttling of the protein between the cytoplasm and nucleus|
|Tissue Location||Mainly restricted to pluripotent cells of the developing embryo, to oocytes, and to certain regions of the adult brain.|
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Provided below are standard protocols that you may find useful for product applications.
Osada N.,et al.Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases.
Carninci P.,et al.Science 309:1559-1563(2005).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Dejosez M.,et al.Cell 133:1162-1174(2008).
Dejosez M.,et al.Cell 134:692-692(2008).
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