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>   home   >   Products   >   Primary Antibodies   >   Eif2c3 antibody - N-terminal region   

Eif2c3 antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - Eif2c3 antibody - N-terminal region AI14328

    WB Suggested Anti-Eif2c3 Antibody Titration: 1.0 μg/ml
    Positive Control: Mouse Pancreas
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8CJF9
Other Accession NM_153402, NP_700451
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Chicken, Horse, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 97kDa
Additional Information
Gene ID 214150
Alias Symbol AW048688, Ago3, C130014L07Rik, Eif2c3
Other Names Protein argonaute-3 {ECO:0000255|HAMAP-Rule:MF_03032}, Argonaute3 {ECO:0000255|HAMAP-Rule:MF_03032}, mAgo3, Argonaute RISC catalytic component 3, Eukaryotic translation initiation factor 2C 3 {ECO:0000255|HAMAP-Rule:MF_03032}, eIF-2C 3 {ECO:0000255|HAMAP-Rule:MF_03032}, eIF2C 3 {ECO:0000255|HAMAP-Rule:MF_03032}, Piwi/argonaute family protein meIF2C3, Ago3, Eif2c3
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Eif2c3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsEif2c3 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Ago3
Synonyms Eif2c3
Function Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Proposed to be involved in stabilization of small RNA derivates (riRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent riRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4.
Cellular Location Cytoplasm, P-body {ECO:0000255|HAMAP- Rule:MF_03032}
Citations (0)

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Doi N.,et al.Curr. Biol. 13:41-46(2003).
Carninci P.,et al.Science 309:1559-1563(2005).
Church D.M.,et al.PLoS Biol. 7:E1000112-E1000112(2009).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Su H.,et al.Genes Dev. 23:304-317(2009).

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$ 293.00
Cat# AI14328
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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