|Application ||WB, IHC|
|Other Accession||NM_009522, NP_033548|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Horse, Guinea Pig, Dog|
|Alias Symbol||vt, Wnt-3a|
|Other Names||Protein Wnt-3a, Wnt3a, Wnt-3a|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Wnt3a antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Wnt3a antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Ligand for members of the frizzled family of seven transmembrane receptors. Wnt-3 and Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube.|
|Cellular Location||Secreted, extracellular space, extracellular matrix|
|Tissue Location||Dorsal portion of the neural tube (developing roof plate), and mesenchyme tissue surrounding the umbilical veins|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Roelink H.,et al.Genes Dev. 5:381-388(1991).
Tanaka K.,et al.Eur. J. Biochem. 267:4300-4311(2000).
Willert K.,et al.Nature 423:448-452(2003).
Zhang X.,et al.Cell 149:1565-1577(2012).
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