|Other Accession||NM_019464, NP_062337|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Mouse, Rat, Rabbit, Pig, Chicken, Horse, Dog|
|Alias Symbol||AA409932, AI314629, AU015566, Bif-1, KIAA0491, mKIAA0491|
|Other Names||Endophilin-B1, SH3 domain-containing GRB2-like protein B1, Sh3glb1, Kiaa0491|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Sh3glb1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Sh3glb1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be required for normal outer mitochondrial membrane dynamics. Required for coatomer-mediated retrograde transport in certain cells. May recruit other proteins to membranes with high curvature. May promote membrane fusion.|
|Cellular Location||Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Mitochondrion outer membrane; Peripheral membrane protein Note=Association with the Golgi apparatus depends on the cell type|
|Tissue Location||Isoform 1 is widely expressed. Isoform 2 is brain specific|
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Provided below are standard protocols that you may find useful for product applications.
Modregger J.,et al.J. Biol. Chem. 278:4160-4167(2003).
Okazaki N.,et al.DNA Res. 11:205-218(2004).
Carninci P.,et al.Science 309:1559-1563(2005).
Yang J.S.,et al.Nat. Cell Biol. 8:1376-1382(2006).
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