|Other Accession||NM_000362, NP_000353|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Sheep, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Chicken, Sheep, Horse, Bovine, Dog|
|Alias Symbol||HSMRK222, K222, K222TA2, SFD|
|Other Names||Metalloproteinase inhibitor 3, Tissue inhibitor of metalloproteinases 3, TIMP-3, Timp3, Timp-3|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-TIMP3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||TIMP3 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli.|
|Cellular Location||Secreted, extracellular space, extracellular matrix|
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Provided below are standard protocols that you may find useful for product applications.
Wu I.,et al.Gene 168:243-246(1996).
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