|Other Accession||NM_024432, NP_077752|
|Reactivity||Human, Mouse, Rat, Pig, Horse, Yeast, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Chicken, Horse, Bovine, Guinea Pig, Dog|
|Alias Symbol||1200008L11Rik, 2210415J11Rik, AU040909, Ubxd1, Ubxdc2|
|Other Names||UBX domain-containing protein 6, UBX domain-containing protein 1, Ubxn6, Ubxd1, Ubxdc2|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Ubxn6 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Ubxn6 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts in a complex with VCP and cooperates with USP7 in promoting MDM2 deubiquitination and stabilization. MDM2 stabilization leads to MDM2-dependent TP53 degradation (By similarity).|
|Cellular Location||Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes at the centrosome both in interphase and during mitosis.|
|Tissue Location||Widely expressed (at protein level). Highest expression in brain (at protein level)|
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Carim-Todd L.,et al.Biochim. Biophys. Acta 1517:298-301(2001).
Carninci P.,et al.Science 309:1559-1563(2005).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Church D.M.,et al.PLoS Biol. 7:E1000112-E1000112(2009).
Madsen L.,et al.Int. J. Biochem. Cell Biol. 40:2927-2942(2008).
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