|Other Accession||NM_013090, NP_037222|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Chicken, Horse, Bovine, Guinea Pig|
|Other Names||Vesicle-associated membrane protein 1, VAMP-1, Synaptobrevin-1, Vamp1, Syb1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Vamp1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Vamp1 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the targeting and/or fusion of transport vesicles to their target membrane.|
|Cellular Location||Isoform 1: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein. Cell junction, synapse, synaptosome Isoform 3: Mitochondrion outer membrane; Single-pass type IV membrane protein. Note=Isoforms 2 and 3 are found in perinuclear as well as peripheral punctate structures in osteoblasts|
|Tissue Location||Expressed in brain and spleen (at protein level). Isoform 1 expressed at very high level in brain. Even higher level found in spinal cord. Isoform 3 expressed in kidney, spleen and liver. Isoforms 2 and 3 expressed in osteoblasts of trabecular bone. Also expressed in heart|
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Provided below are standard protocols that you may find useful for product applications.
Elferink L.A.,et al.J. Biol. Chem. 264:11061-11064(1989).
Mandic R.,et al.Gene 199:173-179(1997).
Prele C.M.,et al.Exp. Cell Res. 282:24-34(2003).
Friedland D.R.,et al.Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
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