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Rph3a antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P47708 |
| Other Accession | NM_011286, NP_035416 |
| Reactivity | Human, Mouse, Rat, Rabbit, Horse, Guinea Pig, Dog |
| Predicted | Human, Mouse, Rat, Rabbit, Horse, Guinea Pig, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 75kDa |
| Gene ID | 19894 |
|---|---|
| Alias Symbol | 2900002P20Rik, AU022689, AW108370 |
| Other Names | Rabphilin-3A, Exophilin-1, Rph3a |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Rph3a antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Rph3a antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Rph3a |
|---|---|
| Function | Plays an essential role in docking and fusion steps of regulated exocytosis (By similarity). At the presynaptic level, RPH3A is recruited by RAB3A to the synaptic vesicle membrane in a GTP- dependent manner where it modulates synaptic vesicle trafficking and calcium-triggered neurotransmitter release (By similarity). In the post-synaptic compartment, forms a ternary complex with GRIN2A and DLG4 and regulates NMDA receptor stability. Also plays a role in the exocytosis of arginine vasopressin hormone (By similarity). |
| Cellular Location | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:P47709}. Cell projection, dendritic spine {ECO:0000250|UniProtKB:P47709}. Postsynaptic cell membrane {ECO:0000250|UniProtKB:P47709}. Membrane {ECO:0000250|UniProtKB:P47709}; Peripheral membrane protein {ECO:0000250|UniProtKB:P47709} |
| Tissue Location | Specifically expressed in brain. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Inagaki N.,et al.Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases.
Inagaki N.,et al.J. Biochem. 116:239-242(1994).
Fukuda M.,et al.J. Biol. Chem. 278:15373-15380(2003).
Munton R.P.,et al.Mol. Cell. Proteomics 6:283-293(2007).
Coudevylle N.,et al.J. Biol. Chem. 283:35918-35928(2008).
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