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OPRL1 antibody - middle region

Rabbit Polyclonal Antibody

  • WB - OPRL1 antibody - middle region AI14423

    Host: Rabbit
    Target Name: WT1
    Sample Tissue: 721_B
    Antibody Dilution: 1.0μg/mlOPRL1 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P79292
Other Accession NM_182647, NP_872588
Reactivity Human, Mouse, Rat, Rabbit, Pig, Goat, Sheep, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Chicken, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 41kDa
Additional Information
Gene ID 397364
Alias Symbol KOR-3, MGC34578, NOCIR, OOR, ORL1
Other Names Nociceptin receptor, K3 opiate receptor, Kappa-type 3 opioid receptor, KOR-3, ORGC, Orphanin FQ receptor, OPRL1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-OPRL1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsOPRL1 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name OPRL1
Function G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin (By similarity).
Cellular Location Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle Note=Ligand binding leads to receptor internalization into cytoplasmic vesicles, decreasing the amount of available receptor at the cell surface. Internalization requires phosphorylation at Ser-363. Can recycle to the cell membrane (By similarity)
Tissue Location Detected in brain cortex, stomach, ileum, jejunum and colon.
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Osinski M.A.,et al.Eur. J. Pharmacol. 365:281-289(1999).

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$ 293.00
Cat# AI14423
(40 western blots)
Availability: 2-3 days
Bulk Size
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