|Other Accession||NM_019303, NP_062176|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Goat, Horse, Bovine, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Pig, Goat, Horse, Bovine, Dog|
|Alias Symbol||CYP4502F4, Cyp2f1|Cyp2f2, Cyp2f1, Cyp2f2|
|Other Names||Cytochrome P450 2F2, 1.14.14.-, CYPIIF2, Cytochrome P450-NAH-2, Naphthalene dehydrogenase, Naphthalene hydroxylase, Cyp2f2, Cyp2f4|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Cyp2f4 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Cyp2f4 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the regio- and stereoselective transformation of naphthalene to trans-1R-hydroxy-2R-glutathionyl- 1,2-dihydronaphthalene in the presence of glutathione and glutathione S-transferases. It specifically catalyzes the production of a very reactive and potentially toxic intermediate, the 2R,2S arene oxide, that is associated with necrosis of the unciliated bronchiolar epithelial cells or Clara cells in lung.|
|Cellular Location||Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein|
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