|Other Accession||NM_032856, NP_116245|
|Reactivity||Human, Rabbit, Horse, Dog|
|Alias Symbol||FLJ14888, HSPC264|
|Other Names||WD repeat-containing protein 73, WDR73|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-WDR73 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||WDR73 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in the regulation of microtubule organization and dynamics (PubMed:25466283).|
|Cellular Location||Cytoplasm, cytosol. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Cleavage furrow. Note=During interphase, located in the cytosol. During mitosis, accumulates at the spindle poles and microtubule asters and later in the cleavage furrow|
|Tissue Location||Expressed in kidney and brain. In the kidney, expressed in glomeruli, most probably in podocytes, and in tubules (at protein level). In the brain, expressed in the cerebellum, with high levels in Purkinje cells and their projecting axons, in the deep cerebellar nuclei and in pyramidal neurons of the cerebral cortex (at protein level). In the white matter, mainly present in astrocytes, but not in oligodendrocytes (at protein level). Also highly expressed in endothelial cells of cerebral capillaries (at protein level).|
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Provided below are standard protocols that you may find useful for product applications.
Zhang Q.-H.,et al.Genome Res. 10:1546-1560(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
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