|Other Accession||NM_031281, NP_112571|
|Alias Symbol||BXMAS1, CD307, DKFZp667E2019, DKFZp667F216, FCRH5, FLJ00333, FLJ00397, IRTA2, MGC119590, MGC119592, MGC119593, PRO820|
|Other Names||Fc receptor-like protein 5, FcR-like protein 5, FcRL5, BXMAS1, Fc receptor homolog 5, FcRH5, Immune receptor translocation-associated protein 2, CD307e, FCRL5, FCRH5, IRTA2|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-FCRL5 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||FCRL5 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein|
|Tissue Location||Expressed in marginal zone B-cells, immunoblasts, tonsillar germinal center centrocytes and in the intraepithelial and interfollicular regions of the tonsil Expressed in many lymphoma cell lines and on hairy cell leukemia cells. Isoform 1, isoform 3, isoform 4 and isoform 5 are detected in lymph node, spleen, bone marrow, and small intestine with preponderance of isoform 3. Expressed in mature and memory B-cells and down-regulated in germinal center cells (at protein level)|
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Provided below are standard protocols that you may find useful for product applications.
Nakayama Y.,et al.Biochem. Biophys. Res. Commun. 285:830-837(2001).
Hatzivassiliou G.,et al.Immunity 14:277-289(2001).
Davis R.S.,et al.Proc. Natl. Acad. Sci. U.S.A. 98:9772-9777(2001).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
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