|Other Accession||NM_000128, NP_000119|
|Reactivity||Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog|
|Alias Symbol||FXI, MGC141891|
|Other Names||Coagulation factor XI, FXI, 220.127.116.11, Plasma thromboplastin antecedent, PTA, Coagulation factor XIa heavy chain, Coagulation factor XIa light chain, F11|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-F11 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||F11 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX.|
|Tissue Location||Isoform 2 is produced by platelets and megakaryocytes but absent from other blood cells|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Fujikawa K.,et al.Biochemistry 25:2417-2424(1986).
Asakai R.,et al.Biochemistry 26:7221-7228(1987).
Hsu T.-C.,et al.J. Biol. Chem. 273:13787-13793(1998).
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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