|Other Accession||NM_000128, NP_000119|
|Reactivity||Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog|
|Alias Symbol||FXI, MGC141891|
|Other Names||Coagulation factor XI, FXI, 126.96.36.199, Plasma thromboplastin antecedent, PTA, Coagulation factor XIa heavy chain, Coagulation factor XIa light chain, F11|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-F11 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||F11 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX.|
|Tissue Location||Isoform 2 is produced by platelets and megakaryocytes but absent from other blood cells|
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Provided below are standard protocols that you may find useful for product applications.
Fujikawa K.,et al.Biochemistry 25:2417-2424(1986).
Asakai R.,et al.Biochemistry 26:7221-7228(1987).
Hsu T.-C.,et al.J. Biol. Chem. 273:13787-13793(1998).
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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