|Other Accession||NM_014628, NP_055443|
|Reactivity||Human, Pig, Horse, Dog|
|Alias Symbol||CMT2, KIAA0110, MGC11282, RP1-261G23.6|
|Other Names||MAD2L1-binding protein, Caught by MAD2 protein, MAD2L1BP, CMT2, KIAA0110|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-MAD2L1BP antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||MAD2L1BP antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex.|
|Cellular Location||Nucleus. Cytoplasm, cytoskeleton, spindle. Note=During early mitosis, unevenly distributed throughout the nucleoplasm. From metaphase to anaphase, concentrated on the spindle|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Nagase T.,et al.DNA Res. 2:37-43(1995).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Mungall A.J.,et al.Nature 425:805-811(2003).
Li W.B.,et al.Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases.
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