|Other Accession||NM_014628, NP_055443|
|Reactivity||Human, Pig, Horse, Dog|
|Alias Symbol||CMT2, KIAA0110, MGC11282, RP1-261G23.6|
|Other Names||MAD2L1-binding protein, Caught by MAD2 protein, MAD2L1BP, CMT2, KIAA0110|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-MAD2L1BP antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||MAD2L1BP antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex.|
|Cellular Location||Nucleus. Cytoplasm, cytoskeleton, spindle. Note=During early mitosis, unevenly distributed throughout the nucleoplasm. From metaphase to anaphase, concentrated on the spindle|
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Provided below are standard protocols that you may find useful for product applications.
Nagase T.,et al.DNA Res. 2:37-43(1995).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Mungall A.J.,et al.Nature 425:805-811(2003).
Li W.B.,et al.Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases.
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