|Other Accession||NM_005759, NP_005750|
|Reactivity||Human, Mouse, Rat, Rabbit, Horse, Yeast, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Pig, Horse, Yeast, Bovine, Guinea Pig, Dog|
|Alias Symbol||ABI-2, ABI2B, AIP-1, AblBP3, SSH3BP2, argBPIA, argBPIB|
|Other Names||Abl interactor 2, Abelson interactor 2, Abi-2, Abl-binding protein 3, AblBP3, Arg-binding protein 1, ArgBP1, ABI2, ARGBPIA|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-ABI2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||ABI2 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Regulates ABL1/c-Abl-mediated phosphorylation of MENA.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Dai Z.,et al.Genes Dev. 9:2569-2582(1995).
Ren R.,et al.Submitted (JUL-1995) to the EMBL/GenBank/DDBJ databases.
Wang B.,et al.Oncogene 12:1921-1929(1996).
Kalnine N.,et al.Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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